Pharmacology 2

Unit 1

1. Pharmacology of drugs acting on cardio vascular system

  • Introduction to hemodynamic and electrophysiology
  • Drugs used in congestive heart failure
  • Anti-hypertensive drugs.
  • Anti-anginal drugs.
  • Anti-arrhythmic drugs.
  • Anti-hyperlipidemic


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Unit 2

1. Pharmacology of drugs acting on cardio vascular system

  • Drug used in the therapy of shock.
  • Hematinics, coagulants and anticoagulants.
  • Fibrinolytics and anti-platelet drugs
  • Plasma volume expanders

2. Pharmacology of drugs acting on urinary system

  • Diuretics
  • Anti-diuretics.

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Unit 3

3. Autocoids and related drugs

  • Introduction to autacoids and classification
  • Histamine, 5-HT and their antagonists.
  • Prostaglandins, Thromboxanes and Leukotrienes.
  • Angiotensin, Bradykinin and Substance P. e. Non-steroidal anti-inflammatory agents
  • Anti-gout drugs
  • Antirheumatic drugs


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Unit 4

5. Pharmacology of drugs acting on endocrine system

  • Basic concepts in endocrine pharmacology. b. Anterior Pituitary hormones- analogues and their inhibitors.
  • Thyroid hormones- analogues and their inhibitors.
  • Hormones regulating plasma calcium level- Parathormone, Calcitonin and Vitamin-D.
  • Insulin, Oral Hypoglycemic agents and glucagon.
  • ACTH and corticosteroids.


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Unit 5

5. Pharmacology of drugs acting on endocrine system

  • Androgens and Anabolic steroids.
  • Estrogens, progesterone and oral contraceptives.
  • Drugs acting on the uterus.

6. Bioassay

  • Principles and applications of bioassay.
  • Types of bioassay
  • Bioassay of insulin, oxytocin, vasopressin, ACTH,d-tubocurarine,digitalis, histamine and 5-HT

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