Medicinal Chemistry 2 - Unit 1

Syllabus

Antihistaminic agents

Histamine, receptors and their distribution in the humanbody


H1-antagonists: Diphenhydramine hydrochloride\*, Dimenhydrinate, Doxylamines cuccinate, Clemastine fumarate, Diphenylphyraline hydrochloride, Tripelenamine hydrochloride, Chlorcyclizine hydrochloride, Meclizine hydrochloride, Buclizine hydrochloride, Chlorpheniramine maleate, Triprolidine hydrochloride\*, Phenidamine tartarate, Promethazine hydrochloride\*, Trimeprazine tartrate, Cyproheptadine hydrochloride, Azatidine maleate, Astemizole, Loratadine, Cetirizine, Levocetrazine Cromolyn sodium

H2-antagonists: Cimetidine\*, Famotidine, Ranitidin.

Gastric Proton pump inhibitors: Omeprazole, Lansoprazole, Rabeprazole, Pantoprazole


Anti-neoplastic agents

Alkylating agents: Meclorethamine\*, Cyclophosphamide, Melphalan, Chlorambucil, Busulfan, Thiotepa

Antimetabolites: Mercaptopurine\*, Thioguanine, Fluorouracil, Floxuridine, Cytarabine, Methotrexate\*, Azathioprine

Antibiotics: Dactinomycin, Daunorubicin, Doxorubicin, Bleomycin

Plant products: Etoposide, Vinblastin sulphate, Vincristin sulphate

Miscellaneous: Cisplatin, Mitotane.


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Unit 1, Medicinal Chemistry 2, B Pharmacy 5th Sem, Carewell Pharma
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