Medicinal Chemistry 2 - Unit 5

Syllabus

Antidiabetic agents:

Insulin and its preparations

Sulfonyl ureas: Tolbutamide\*, Chlorpropamide, Glipizide, Glimepiride.

Biguanides: Metformin.

Thiazolidinediones: Pioglitazone, Rosiglitazone

Meglitinides: Repaglinide, Nateglinide.

Glucosidase inhibitors:Acrabose, Voglibose.

Local Anesthetics: SAR of Local anesthetics

Benzoic Acid derivatives: Cocaine, Hexylcaine, Meprylcaine, Cyclomethycaine, Piperocaine.

Lidocaine/Anilide derivatives: Lignocaine, Mepivacaine, Prilocaine, Etidocaine.

Miscellaneous: Phenacaine, Diperodon, Dibucaine.*

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